Cook the elbow macaroni according to package directions until al dente. Drain and rinse with cold water.
Dice the pepperoni, red onion, and celery.
In a large bowl, whisk together the mayonnaise, sour cream, Italian dressing, white wine vinegar, sugar, Dijon mustard, garlic powder, smoked paprika, salt, and pepper.
Add the cooked macaroni, diced pepperoni, cheddar cheese, red onion, celery, and sweet pickle relish to the bowl with the dressing.
Gently toss everything together until well combined.
Cover and refrigerate for at least 1 hour before serving.
Notes
Adjust the seasonings to your liking. Add a pinch of red pepper flakes for extra spice.
Keyword BBQ, Guy Fieri, Macaroni Salad, Pepperoni, Potluck